Kokilaben Dhirubhai Ambani Hospital is a tertiary-care hospital in Four Bungalows, Mumbai, India. The hospital is named after Kokilaben Ambani, wife of industrialist Dhirubhai Ambani, who was the founder of Reliance Industries.

The 750 bed multi-speciality hospital became operational in the first week of 2009. The project was initiated in 1999 by Nitu Mandke as a large-scale heart hospital, but ran into troubles after his death in 2003. Subsequently, it was completed by the Anil Ambani-led Reliance ADA group.^[1] The hospital has boasted of many firsts not only in India but also in Asia. Kokilaben Dhirubhai Ambani Hospital has the first 3-room intra-operative MRI suite (IMRIS) in Asia, Asia's first EDGE Radiosurgery system from Varian Medical Systems, India's 1st Spine Surgery Suite featuring the O-arm and many more.

• Kokilaben Dhirubhai Ambani Hospital, one of the most modern and state-of-the-art multi-specialty tertiary care hospitals, was launched in 2008 by Reliance Group.
• The Hospital is accredited by the Joint Commission International (JCI) and the National Accreditation Board for Hospitals & Healthcare Providers (NABH) , College of American Pathology (CAP) Accreditation, USA, National Accreditation Board for Testing and Calibration Laboratories (NABL) Accreditation, India
• Kokilaben is the only hospital in Mumbai with Full Time Specialist System (FTSS) ensuring easy availability and access to dedicated specialists exclusively attached to Kokilaben Dhirubhai Ambani Hospital.
• Hospital uses Protocol and Care Pathway based treatment models to ensure the best outcomes for patients.
• Kokilaben Hospital offers state-of-the-art, non-invasive treatment for a wide range of cancers and other potentially debilitating conditions, without harming nearby healthy tissue and without involving the traditional surgical procedure.
• They are the first in India to have a 3-room Intra-operative MRI Suite (IMRIS), a diagnostic and imaging solution where the patient is never moved.
• Novalis TX at Kokilaben Hospital is among the world's first whole radiosurgery systems for indications in the brain, liver, pancreas, prostate and lung.
• Kokilaben Dhirubhai Ambani Hospital has set up 18 sophisticated cancer care centres.
• Over 6300 complex cancer surgeries have been performed with excellent outcomes.
• It is the only hospital India to perform the fastest 1000 Robotic Surgeries within 48 months of Launch.
• Kokilaben Hospital has been awarded the smartest hospital building in India by Honeywell and the Times of India for its use of power consumption control, use of natural resources, worker safety, personal protection, indoor environment quality and control energy-efficient appliances and fixtures, uninterrupted power supply, fire detection and notification, as well as surveillance and intrusion.
• In a all India survey undertaken by The Times of India, Kokilaben Dhirubhai Ambani Hospital has been ranked no. 1 in western India for Dermatology, Diabetology, Plastic/ Cosmetic Surgery and Trichology.
• Hospital is visited by renowned doctors like Dr Tanu Singhal, Dr Jawahar Mansukhani and Dr Chaitali Ghandhi etc.

The hospital courted controversy in 2014 when it offered incentives to doctors for referring patients. It later apologised to the Maharashtra Medical Council.

In 2016, the hospital announced that it would be setting up 18 cancer-care centres in rural Maharashtra, under the name Reliance Cancer Centre's that will be operated and managed by Kokilaben Dhirubhai Ambani Hospital.